Cytiva Cadence Virus Inactivation System
The Cadence™ Virus Inactivation (VI) system is a fully automated system that provides the ability to perform low pH virus inactivation to an incoming elution stream continuously, with minimal operator involvement.
The system will collect the elution stream from a continuous chromatography system. However, it can easily process as standalone system or with a batch chromatography system.
The system automates sequentially: eluate collection, pH decrease, hold at low pH, pH neutralization, and the transfer to the next unit operation.
The system comprises of a control unit which attaches to one or two system specific Allegro™ single-use mixers dependent on the application. The specification of the manifolds currently supports 24 hours continuous operation.
- Low pH virus inactivation
- Designed for integrated unit operation
- Fully automated for true continuous processing
- Reduced risk of operator error
- Ability to operate in batch or continuous mode for flexible facility fit
- Automates sequentially